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A COMPREHENSIVE REVIEW ON ANTI-CANCER PROPERTIES AND MEDICINAL VALUES OF ARTOCARPUS HETEROPHYLLUS
Authors
AMRITHA,FATHIMA MIRFATH T,MIZAJ JASIRA U,Dr.ANSU MARRY KURIAKOSE
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Keywords
Artocarpous Heterophyllus, Phytochemicals, jack Fruit
Abstract
Research is focusing on the search for new types of natural chemotherapeutic agents derived from plants
which are proving to be excellent sources of new compounds. This review aimed to highlight the
information regarding physicochemical properties, Chemical Composition, Anticancer properties and
their administrations of jackfruit. Artocarpus heterophyllus shows anticancer properties due to the
presence of phytochemicals like lignans, saponins, flavonoids carotenoids, tannins, volatile acid steroids
and also the properties such as anti-oxidant, anthelminthic, anti-inflammatory, anti-bacterial,
anti-viral activities. The phytochemical constituent artocarpine have effect on cancer cells. Target specific
agents that are capable of inducing selective apoptosis of cancer cells but are harmless to the normal
cells are receiving considerable attention in the field of cancer prevention and therapy. The flavonoid
compound artonine B have anti-cancerous effect on human cancer cells. Different studies are performed
on this topic and reported. Also, further researches and studies are ongoing.
OBJECTIVE: The objective of this article is to provide a detailed and systematic knowledge on the
anti-cancer property of Artocarpus heterophyllus (jack fruit) and its medicinal values.
METHODS: A vigorous, maximum sensitive and online search of the literature was performed in
published articles in the last 20 years (JUNE 2000-JUNE 2020). The databases searched were MEDLINE
(via PubMed) and Cochrane Library.
CONCLUSION: Cancer is becoming a high profile disease in developed and developing worlds. In 2017
the WHO published that in 2015, 7.6 million people died from cancer related diseases with the majority
of these people living in low-income countries. the demand for a cure and the prevention of cancer is
extremely high. Experimental studies performed in the past suggest that, jackfruit possesses diverse
medicinal uses including antioxidant, anti-inflammatory, antimicrobial, ant cariogenic, antineoplastic
and hypoglycemic effects, inhibits melanin biosynthesis, possesses wound healing properties, and causes
a transient decrease in the sexual performance. Target specific agents that are capable of inducing
selective apoptosis of cancer cells, but are harmless to normal cells are receiving considerable attention
in the fields of cancer prevention and therapy. Therefore, Artocarpus heterophyllus is a candidate for
development as a Chemo preventive agent.
IJCRT's Publication Details
Unique Identification Number - IJCRT2408001
Paper ID - 266948
Author type - Indian Author
Page Number(s) - a1-a12
Pubished in - Volume 12 | Issue 8 | August 2024
DOI (Digital Object Identifier) -
No Of Downloads - 275
Author Country - India, 679335, Nellaya, Nellaya, 679335, Pharmacy All
Publisher Name - IJPUBLICATION | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Published Paper PDF : - http://www.ijcrt.org/papers/IJCRT2408001
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AMRITHA,FATHIMA MIRFATH T,MIZAJ JASIRA U,Dr.ANSU MARRY KURIAKOSE, "A COMPREHENSIVE REVIEW ON ANTI-CANCER PROPERTIES AND MEDICINAL VALUES OF ARTOCARPUS HETEROPHYLLUS", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.12, Issue 8, pp.a1-a12, August 2024, Available at :http://www.ijcrt.org/papers/IJCRT2408001.pdf
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