Volume 12 | Issue 9 |

 Abstract

Transdermal drug delivery system is the system in which the delivery of the active ingredients of the drug occurs by means of skin. Transdermal distribution establishes the most important channels for a revolutionary medication delivery method. Basically, the Transdermal drug delivery system is a non-invasive method of drug administration. The drug delivery method will incorporate the drug to be delivered into polymeric membranes, which then diffuse the drug into skin at planned and controlled rate. The various advantages of drug delivery of transdermal are oral and injection. Transdermal administration entails to pushing the patch containing a medicinal substance onto the skin, which is both convenient and painless, as well as therapeutic first-pass metabolism. From throughout the body, an adhesive patch is designed to deliver a specific dose of medication into the bloodstream and through the skin. The Transdermal drug delivery has several advantages over other routes of administration, and for some instance, its less invasive, patient-friendly, and it is able to do the bypass of first-pass metabolism and the destructive acidic environment of the stomach that will occurs upon the oral ingestion of drugs. For decades, the transdermal patches were used to deliver drugs such as nicotine, nitroglycerin, fentanyl and clonidine to treat various diseases or conditions. The goal of this review is to know the history and origination of the transdermal patches, the design and usage of medical patches in transdermal drug delivery, with a focus on the recent advances in the innovation and technology that led to the emergence of smart, dissolvable/biodegradable, high-loading/release, as well as 3D-printed patches.

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 Keywords

Transdermal, non-invasive, adhesive patch, first pass metabolism, nicotine, fentanyl, nitroglycerin, clonidine, smart patches, high loading release, 3D printed patches

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Digital technology [1] has transformed people's lives significantly, particularly in rural areas, by empowering and connecting them. According to analysts, the Digital India plan could boost GDP up to $3 trillion by 2025. It can play a key role in macro-economic factors such as GDP growth, employment generation, labor productivity, growth in several businesses, and revenue leakages for the Government. a 12% increase in mobile and broadband penetration increases the per capita GDP by 0.81% and 1.38% respectively in developing countries. India is the 2nd largest telecom market in the world with 950 million wireless subscribers and the world's 3rd largest Internet market with almost 300 million broadband users. There is still a huge economic opportunity in India as the tele-industry in rural India is only 45% where more than 65% of the population lives. Thus, the growth and development of the rural economy are imperative for inclusive development and overall growth of the country. India's rural areas are brimming with young, tech-savvy individuals who possess immense potential to drive digital innovation and entrepreneurship. Additionally, Rural people's access to education and training is often limited by financial barriers and lack of physical infrastructure in rural and remote areas. This is where m-Education / digital services can play an important role by reaching remote masses. To address this gap, we propose the "Empowering Young Digital Innovators" [17] project, which aims to provide comprehensive business development training and mentorship to rural youth, empowering them to become the digital change-makers of tomorrow. This project aims to address this gap by providing young digital innovators with training and support in business development, including business model development, marketing, and financial management. Social sectors such as healthcare, and banking are unable to reach out to the citizens due to obstructions and limitations such as middleman, illiteracy, ignorance, poverty, lack of funds, information and investments. Digital technologies have the potential to create new markets and business models in rural India, [30] but rural youth often lack the knowledge and skills to capitalize on these opportunities. Business development training can help rural youth create sustainable and scalable businesses while contributing to the overall development of rural communities.

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 Keywords

Digital India, Enterprise, Rural India, Digital Innovation, Digital Platforms, Empowerment

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The aim of this Paper is to bring to light the significance of Aprthak-siddhi concept in Sri Ramanuja's Philosophy.The purpose of this paper is to analyze the three realities ie; God, soul and world are connected to each other or distinct from each other by means of Aprthak-siddhi.To find out whether external relation or internal relation holds good from the Visistadvaita's point of view is the crux of his philosophy.

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 Keywords

Aprthak-siddhi, Samavaya, Samyoga, Ayuta-siddha, Svarupa-Sambandha, Cit, Acit, Sarira, Sariri, Visista, Brahman, Jiva, padarthas, Nitya.

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This study investigates the dynamic relationship between the Indian gold market and the equity market, represented by BSE Sensex and Nifty 50, over a decade-long period. Employing a comprehensive methodological approach, including descriptive statistics, correlation analysis, regression modeling, and ARIMA forecasting, this research aims to uncover the underlying patterns and dependencies among these asset classes. The study finds a statistically significant negative correlation between gold and stock market returns, suggesting that they tend to move in opposite directions. However, regression analysis reveals that the impact of gold price changes on stock market indices is relatively limited, indicating the presence of other influential factors. The ARIMA model provides short-term forecasts for gold prices and stock market indices, offering insights into potential future trends.

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Keywords: Gold Market, Nifty 50, BSE Sensex

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Creative Commons Attribution 4.0 and The Open Definition

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Women empowerment in India is a multifaceted process involving the enhancement of women's access to education, economic opportunities, political participation, and healthcare, ultimately enabling them to contribute meaningfully to society. This article explores the current state of women empowerment in India, focusing on opportunities in various fields such as education, economic participation, and healthcare. It also examines the significant challenges faced by both working and household women, including the dual burden of professional and domestic responsibilities, workplace discrimination, and societal and cultural barriers. The role of government policies in promoting women empowerment is analyzed, with a focus on initiatives like Beti Bachao Beti Padhao, Pradhan Mantri Mudra Yojana, and the reservation of seats for women in local governance. Despite the progress made, persistent challenges such as gender inequality, health-related issues, and economic dependence underscore the need for continued efforts to create an enabling environment for women. The article concludes by emphasizing the importance of addressing socio-cultural norms and strengthening policy implementation to achieve true women empowerment in India.

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Creative Commons Attribution 4.0 and The Open Definition

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Women empowerment, India, Gender equality, Education, Economic participation, Political representation, Healthcare, Government policies, Social barriers, Women's rights

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Creative Commons Attribution 4.0 and The Open Definition

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Automated Summarization and Sentiment Analysis of Streaming Content The YouTube Video Analyzer addresses the growing need for efficient analysis of streaming content. This tool utilizes natural language processing (NLP) and machine learning to automatically extract and summarize information from YouTube videos and viewer comments. It integrates sentiment analysis, Google's GenerativeAI Gemini Pro for summarization, and leverages YouTube's official APIs for comprehensive content analysis. This allows users to quickly grasp video content and viewer sentiment, empowering researchers, creators, and enthusiasts to navigate the vast world of streaming content with greater ease. The YouTube Video Analyzer represents a significant step forward for automated content analysis in the online streaming landscape.

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Creative Commons Attribution 4.0 and The Open Definition

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YouTube Video Analyzer, Content Summarization, Natural Language Processing (NLP), TextBlob, Streamlit, Google GenerativeAI, Sentiment Analysis, Viewer Comments, Machine Learning, Digital Content Analysis, Public Opinion

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Ayurveda emphasizes on maintaining the good health i.e. Swasthya of a healthy being and also deals with treatment of various diseases (1). Like many other problems in pediatric age group, Napkin rash is a commonest concern. Prevalence of Napkin rash has been reported from 7-35% in the first one year of life. Most cases occur between 9-12 month of age (2). In Ayurvedic classics this condition is referred to as Ahiputana, Gudakuttaka, Mathrukadosha, Prishtaru and Anamaka. It is caused by improper care of infants and children with diapering and is also said to be stanyadushtijanya vyadi (caused by vitiated breast milk) (3) The disease is characterized by Pidika (papulovesicular lesion), Kandu (Irritability due to itching), Strava (discharge), Varna (skin color over perianal region) erythema, papules, pustules, ulcer, erosions, etc in the anal region. The condition has close resemblance with diaper dermatitis. This condition even worsens with Atisara,Grahani Rogas, Putana Graha, Ksheeralasaka, Charmadala.

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Ahiputana, Shatdhauta Ghruta, Napkin rash.

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Dysmenorrhoea is one of the most widely common gynecological problems among all the females and also known as cramping pain and it occurs in the lower abdomen just before or during menstruation. The menstrual symptoms are a broad collection of affective and somatic concerns that occur around the time of menses. The effect of Dysmenorrhoea is very wide, however managing the problem is important.

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Creative Commons Attribution 4.0 and The Open Definition

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Dysmenorrhoea, Menstrual symptoms, Abdomen pain, school, girls' student.

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Creative Commons Attribution 4.0 and The Open Definition

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Startup plays a pivotal role in the success and growth of new ventures, yet navigating the financial landscape can be daunting for entrepreneurs. This research paper provides a comprehensive analysis of startup, focusing on the strategies employed by startups to raise capital, the challenges they encounter, and the opportunities available to fuel their growth. Through an exploration of theoretical frameworks, empirical studies, and real-world examples, this paper aims to offer insights into effective financial management for startups and foster a deeper understanding of the startup finance ecosystem. It examines the factors that contribute to a startup's success, including a strong value proposition, a well-defined target market, and a skilled team. The paper also explores the current global startup ecosystem, highlighting trends and geographical variations. Finally, it discusses the impact of startups on society, including job creation, economic development, and technological advancement.

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Creative Commons Attribution 4.0 and The Open Definition

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Startup India, Startups

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Creative Commons Attribution 4.0 and The Open Definition

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This study investigates the impact of digital education on children's cognitive development and social skills. Using a sample of 300 teachers from government and private schools in Jalandhar city, the research explores how digital tools influence various aspects of student development. The analysis reveals that screen time strongly correlates with cognitive development, suggesting that digital resources can enhance learning abilities. However, the impact on social skills, parental involvement, and learning outcomes is less pronounced. Findings show that while digital education is beneficial for cognitive growth, its effects on social interactions and overall learning experiences need more attention. The study highlights the importance of balancing digital and traditional educational methods to optimize development and suggests increased parental engagement and professional training for educators. Overall, the research emphasizes a holistic approach to integrating digital tools in education, aiming to improve both cognitive and social outcomes for children.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Digital Education, Cognitive Development, Social Skills, Screen Time, Parental Involvement

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Creative Commons Attribution 4.0 and The Open Definition