Volume 11 | Issue 6 |

 Abstract

Pharmacovigilance is defined by the World health organization as "the science and activities relating to the detection, assessment, understanding, assessment and prevention of adverse effects or any other drug related problems". Pharmacovigilance currently raises awareness in India about adverse drug reactions (ADR), and this review provides data on effectiveness in addressing existing issues. This essay's description of living in India, its difficulties, and its prospects for the future perfectly encapsulated the ideal and approach utilized in pharmacovigilance. In this article's goals are to make the argument for the importance of pharmacovigilance, to document its development and eventual recognition as a significant field of medical knowledge, and to discuss its effects on patient welfare and overall public health.

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 Keywords

Pharmacovigilance, Adverse drug reaction, Uppsala monitoring center, Drug safety, World Health Organization, Pharmacovigilance Program in India (PvPI)

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The procurement process plays a significant role and improvements can be made for increasing the productivity of the materials team thereby resulting in improvement in production. Being a public sector, following procurement guidelines viz: tendering, evaluation, conducting auctions amongst technically & commercially qualified bidders, and meeting the plant requirements on scheduled time is a challenging task for the company. The present study analyses the dimensions of the effectiveness of the input procurement system and also examines general information about the suppliers. The study stated that the identified five dimensions of the input procurement system have a positive opinions by the respondents. The results indicate that the dimensions transparency, adaptability, ease of, and grievance redressal are significantly associated while the timely payment is not significantly associated with the input procurement system.

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 Keywords

Adaptability, Effectiveness, Grievance, Procurement, System, Transparency

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This study investigates how Basalt Fiber Reinforced Self-Compacting Concrete (BFRSCC) performs in exterior beam-column joints subjected to positive quasi-static loading. The research focuses on understanding the behavior of basalt fibers when combined with M30 grade Self-Compacting Rubberized Concrete (SCRC) and 12mm chopped Basalt fiber. The aim is to provide valuable insights for the design and construction industry on the use of BFRSCC in reinforced concrete structures, following the principles of strong column weak beam theory for ensuring structural integrity. Experimental findings consistently show that the initial crack occurs near the bottom of the beam close to the joint and progresses upward during loading cycles, resulting in flexural cracks and beam hinging at the joint interface. Shear failure is identified as the primary mechanism leading to failure. By incorporating smaller proportions of crumb rubber and basalt fiber, the ductility of the specimens is improved in terms of displacement and stiffness. Crumb rubber inclusion enhances crack load and ultimate deflection, while basalt fiber reinforcement enhances crack load, ultimate load, and ultimate deflection. However, careful selection of the fiber content is crucial to balance the load-carrying capacity and stiffness. Challenges in meeting flowability requirements limit the exploration of higher fiber percentages, calling for further research. The study evaluates ductility and reveals significant enhancements with crumb rubber and basalt fiber. The findings contribute to construction practices and provide guidance for engineers, researchers, and practitioners involved in the construction of resilient and durable moment-resisting frame structures. Future research can explore alternative mix designs and examine the behavior of BFRSCC under different loading conditions to expand its practical applications.

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 Keywords

Basalt Fiber Reinforced Self-Compacting Concrete; Beam-Column Joints; Positive Quasi-Static Loading; Ductility; Crumb Rubber; Structural performance

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 Abstract

The mucus layer that covers the mucosal epithelial surface interacts with mucoadhesive drug delivery systems, and mucin molecules lengthen the dosage form's stay at the absorption site. The situation in which two materials, at least one of which is biological in nature, are kept together for extended periods of time by interfacial forces is known as bioadhesion. Since mucosal layer lines many parts of the body, such as the gastrointestinal tract, urogenital tract, vaginal tract, eye, ear, and nose, it represents prospective sites for the attachment of any bioadhesive systems. The mucoadhesive bilayer tablets include two different therapeutic molecules that each exhibit a unique set of effects at their respective locations.

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mechanism of permeation, bioadhassion, polymer, bilayer tablet, NDDS, Novel Drug.

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The sunlight consists of harmful radiations which affects the skin. The Ultraviolet radiations are of 3 types Ultraviolet A, Ultraviolet B and Ultraviolet C. This article gives a detailed review on different types of Ultraviolet radiation. To protect our skin from Ultraviolet radiation sunscreen formulations are used which either absorbs scatters or reflects the radiation. The harmful effects on skin like photo aging, skin cancer, DNA damage are explained. The present review explains the various types of sunscreen formulations and the agents used for the purpose of sun screening. The agents are of two type's physical and chemical sun screening agents. The physical agents which block the sun light and the chemical agents which absorb the sunlight are listed and explained. To know the efficacy of the formulation sun protection factor calculation is done. The equation used to calculate the Sun Protection Factor value is explained in detail. The ultraviolet spectroscopic method is employed to calculate the Sun Protection Factor. The proposed method is found to be easy and rapid for the calculation of Sun Protection Factor values in the in vitro studies. The herbal formulation is more advantageous than the chemical formulation because of its fewer side effects. Few herbal sun screen agents are listed and explained its activity.

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UV radiations, Sunscreen agents, Sun Protection Factor, Herbal sunscreens

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Abstract-- Nowadays, cosmetics are becoming more high demand in daily life and it was used frequently by many of people per year. Mankind uses various products to enhance beauty and elegance to look young and charming. Cosmetics thus play a vital role in human life. Now days, herbal cosmetic are widely used because of the belief that they have fewer side effects and better safety. Hair is one of the primary parts of the body which acts as a protective appendage. The main objective of the present work is to develop an herbal hair serum for general purpose (daily use) using various herbs with this evaluate the characteristics of cosmetic serum and to identify the best formulation of cosmetic serum. Three formulations of cosmetic serum (H1, H2 and H3) with different concentration of excipients have been developed. They were evaluated for its physical appearance, pH, homogeneity test, viscosity, spreadability test and stability test. All the parameters were found to be good and within the standards. Current research has revealed that herbal formulations are effective in enhancing hair consistency. In the mammalian system, the hair follicle is known to be the most significant organ that determines appearance, gender distinction, give violent temperature protection, and plays a part in tone- defense. The youngish generation have begun to suffer from extreme hair loss problems due to numerous life- related changes similar as fatigue, anxiety, input of junk foods, use of diiferent hairstyling/ coloring styles, etc. The loss of hair isn't temporary in utmost cases, but it results in alopia. numerous people suffering from hair loss are in hunt of multiple treatments due to extreme anxiety and pressure, from tradition to traditional and remedial mending to the use of minoxidil and finasteride. To ameliorate hair growth and to help hair loss, hair root activation is needed. Herbal dress are still generally used by average citizens because of smaller side goods and lesser protection and safety profile. The present study was intended to use different sauces to formulate herbal hair serum for general purposes (hair operation).

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: Citrus Sinensis, flaxseed, Nigella sativa, Zingiber officinale, castor oil painting, Trigonella ,Cosmetic, hair, herbs, formulation, effective, etc.

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Face mask use has been identified as one of the most efficient strategies to stop spreading of the COVID-19 epidemic, which has produced a global health disaster. With the increasing demand for mask-wearing in public places, detecting whether individuals are wearing masks or not has become a critical issue. Artificial Intelligence (AI) techniques have emerged as a promising solution for face mask detection. This survey paper provides an impression of recent investigation on the use of AI for face mask detection. The paper first introduces the importance of mask-wearing in preventing COVID-19, and then reviews the state-of-the-art AI techniques used for face mask detection, including deep learning techniques, machine learning techniques, and combined methods. The survey also covers different datasets and evaluation metrics used in the studies. The paper comes to a close with an assessment of upcoming directions for this field of study.

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Artificial Intelligence, Face mask detection, Deep Learning

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single-crystal X-ray study; synthesis; crystal structure; pyrrolidine; fluoro; indoline; C-H...F, C-H...N and N-H...O; hydrogen bonds; ?-stacking; T = 295 K; R factor = 0.0519; wR factor = 0.1549; data-to-parameter ratio = 10.5.

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ABSTRACT: Background: Academic stress is a mental suffering caused by the expected dissatisfaction of academic failure. Whereas emotional intelligence is a personality trait that indicates an individual's ability to comprehend and tolerate one's own emotions as well as those of others. Aim and Objective: The broad aim of the present study was to investigate an empirical-based examination of the relationship among academic stress and emotional intelligence in secondary class students. The objectives of the study were to ascertain if there exist any gender, family structure and single child differences between academic stress and emotional intelligence. Method: The present study aims to investigate emotional intelligence and academic performance of students at the secondary level. Using random sampling technique 200 students, from the secondary level in different systems of education, namely, state, matriculation and central board schools are chosen. The Emotional Intelligence Scale has been used to assess the emotional intelligence and the marks scored yearly performance. The data collected is subjected to statistical analysis, namely, mean, standard deviation, 't'- test, Karl Pearson's Product Moment Correlation Co-efficient 'r'. Result: Results show a positive significant correlation between emotional intelligence and academic performance among the students. Further the students belonging to the central board schools have a higher level of emotional intelligence compared to students in state board but did not differ with students in matriculation board schools at the secondary level. Similarly, students belonging to central board schools are found to perform better in academics compared to students in state and matriculation board schools at the secondary level.

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Keywords: Academic stress, Emotional intelligence, Academic score.

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 Abstract

The uncommon disease aniridie, caused by a mutation in the gene PAX6, affects the whole ocular globe. We present the case of a 37-year-old woman who has bilateral eye pain and is malvoyant, known to have an aniridia, and hypoplasie of the fovea.

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 Keywords

Congenital aniridia;Lens dislocation;Foveal hypoplasia;Cataract.

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