Volume 11 | Issue 6 |

 Abstract

Sunscreen is a chemical compound that helps to protect UV rays.although ultraviolet B light causes sunburn, ultraviolet A may be more harmful to the skin.the occurrence of actinic keratosis,squamous cell carcinoma,melanoma is decreased by routine sunscreen use.chemicals in sunscreen can be either organic or inorganic.sunscreen use has increased as a result of the rising incidence of skin cancer and the photo damaging effects of UV light . Plant's anti oxidant,anti inflammatory,antiseptic, and antibacterial qualities among others are used to protect skin from various pathogens. Sunscreen should be completely able to protect the skin from sun damage and should be chemically insert, non irritating , non toxic phota table and safe. The sun's UVA and UVB radiation causes skin cells to get damaged as a result of the skin producing reactive oxygen species.in order to effectively prevent photo ageing and akin Cancer, sunscreen should be also contain antioxidant agent.A herbal sunscreen cream is made using plant extract, such as Tritium Aestivum L. ( Wheat grass) .Vit E and the polyphenolic drug.

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 Keywords

Herbal sunscreen, SPF, Tritium Aestivum,sun protective, skin burn

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 Abstract

The International Conference on Harmonisation (ICH), the Food and Drug Administration of the United States (FDA), and the Canadian Drug and Health Agency (CDHA) are among the regulatory agencies that place a strong emphasis on the purity standards and the detection of impurities in active pharmaceutical ingredients (APIs). Reagents, heavy metals, ligands, catalysts, other substances like filter aids, charcoal, and the like, degraded end products obtained during or after manufacturing of bulk drugs from hydrolysis, photolytic cleavage, oxidative degradation, decarboxylation, enantiomeric impurity, and so on are just a few of the different sources of impurity in pharmaceutical products. Limits to permissible levels of impurities present in APIs or formulations are gradually being added by the various pharmacopoeias, including the British, American, andIndian versions.For example, capillary electrophoresis, electron paramagnetic resonance, gas-liquid chromatography, gravimetric analysis, high performance liquid chromatography, solid-phase extraction methods, liquid-liquid extraction methods, UV spectroscopy, infrared spectroscopy, supercritical fluid extraction column chromatography, mass spectrometry, nuclear magnetic resonance (NMR) spectroscopy, and others are used to isolate and characterise impurities in pharmaceuticals. Liquid chromatography (LC)-mass spectroscopy (MS), LCNMR, LC-NMR-MS, gas chromatography-mass spectroscopy (GC-MS), and LC-MS are the hyphenated methods used the most frequently for drug impurity profiling. This highlights the significance and necessity of drug impurity profiling in pharmaceutical research.

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 Keywords

Characterization, chromatography, identification, impurities.

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Functional requirements of a product driven by customer leads to the introduction of new materials and manufacturing processes. Development of machining processes i.e. macro and micro are progressing effectively. In order to achieve successive products by conventional machining the consideration of machine tools should be focused. In this paper an overview of tool wear mechanisms, effects of wear on machinability criteria, measurement of tool wear, selection of the tool material & tool geometry is discussed. It can be concluded that combination of tool and workpiece materials, machining parameters such as spindle speed, feed and depth of cut, tool geometry, tool coatings and coolants selection plays major role in conventional machining.

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 Keywords

Machining, Tool Wear, Tool Geometry, Material, Coolants, Coatings.

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 Abstract

A Reinforced Cement Concrete framed structure is a formation of multiple building components such as slabs, beams, columns, and foundations into a single unit. In this type of structure, the transfer of weight occurs sequentially; the beams receive a load from the slabs, then beams give it to the columns, then received it to the lower columns, and ultimately to the foundation. The foundation then transfers the load to the soil. The analysis outputs are applied to validate the structure's accuracy for future use. Nowadays, all types of forces can be calculated by using analysis software. The principal objective of this project is "The Response Spectrum Analysis of Multi-storeyed Commercial Building (G+7) by STAADPRO Software". To design the structure, designers highly recommended the STAADPRO software. In this project, to develop the economic design of the G+7 building through response spectrum analysis Staadpro software is used. Staadpro is the leading design software in present days used by many structural designers. According to the design of IS: 1893 (Part III) seismic design is used to perform the analysis of this structure. The results observed that the multi-storeyed buildings are stiff for earthquake excitation as modal participation

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 Keywords

RCC, Staadpro, G+7 Storey, Software, Analysis

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Today, visual information is the most important information, therefore blind or partially sighted people are at a disadvantage because mandatory avoidable information is not available to them. The aim of this project is to skillfully guide the visually impaired. This system is designed for them to solve an impossible situation that affects the blind. Our system introduces an automatic system that allows them to read text patterns printed on documents. Text models are localized and binarized using OCR. The identification text is converted to sound and given to the user. So work on character recognition. Difficulty recognizing people during a conversation is a huge handicap for those people in many professional and constructive situations. In these devices, smartphones are used to increase the accuracy of face recognition, we have an archetype and face recognition is tested on end users. This system uses a text-to-speech module to generate audio for the blind.

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 Keywords

OpenCV, GTTS, Deep Learning, Pyttsx3, Tkinter, Text to speech

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 Abstract

The word "Stree itself indicates one who does Dharana of Garbha". In Vedas Stree is compared to mother earth as both have the quality of forebearance and reproduction. But nowdays reproductive capacity of women is being greatly challenged by numerous diseases, changed lifestyle ,physical and emotional stress ,which alters the physiology and ends with destruction of H-P-O axis and may lead to many gynecological problems, in them Artavakshaya is one.Aim: The aim of the study is to evaluate the efficacy of KatutrikadiChurna in Artavakshaya.Materials and methods :This is single case study of 26 yrs female suffering from delayed and scanty menses since her menarche .Detailed history with all clinical and laboratory investigations were done,and all reports were normal.so on the basis of symptoms the patient was treated with Katutrikadichurna with AnupanaTilakwatha.Result:After completion of 3 cycle the menses were regular with normal amount .

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Artavakshaya,Oligohypomenorrhoea,Katutrikadichurna,

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The purpose of this research was to develop a novel gastroretentive drug delivery system based on controlled delivery of active agent. Granisetron is an indole derivative having the antiemetic activity. It's a selective serotonin receptor antagonist. Granisetron blocks the action of serotonin at 5HT3 receptors. It also results in Suppression of Chemotherapy-and radiotherapy-induced nausea and vomiting. The incorporation of swellable and natural polymer for binding action and also good water solublility with high molecular weight such as carbopol present it in the gastro retentive floating tablets, which are designed to provide the desired controlled and complete release of drug for prolonged period of time. Lactose was used as filler. Buoyancy was achieved by adding an effervescent mixture of sodium bicarbonate and anhydrous citric acid. Floating tablets were prepared by direct compression method. All the required evaluation parameters such as hardness, friability, drug content uniformity and swelling index were performed and found within the acceptance limit.

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Granisetron, Gastroretentive Drug Delivery System, Floating tablets

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Creative Commons Attribution 4.0 and The Open Definition

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In the early 1900s, Walter Benjamin was utterly perplexed by the integration of photography into an artform. A widely respected essayist, the topic seeped into multiple of his works, leaving modernists and postmodernists with a plethora of views on the ways in which photography overshadows the works and the needs of artists. While 21st century creatives have not only accepted, but flourished in the photographical arts, they are presented with a new technological prowess; Artificial Intelligence (AI). The tool has quickly demonstrated remarkable capabilities across various fields, such as data science, automation, and numerical problem solving. However, its impact on the creative arts and language has resulted in considerable, and necessary debate. The balance between human creativity and unmatched computational power to create a fair contender of 'artwork' is being redefined, and it is time to determine to what extent AI produced work truly constitutes art.

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The Fallibility of AI and Inhibiting Artistic Originality

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The paper presents a prototype for a sign language interpreter which can communicate with American Sign Language (ASL). Sign language serves as a visual stimulation of speech and language development. It helps to reduce negative social behaviors, increase social interactions, and develop cognitive structures. With early introduction, sign language provides emotional, social, and academic support for language development. The reliable paradigm is based on building a user-hand gesture-only human-computer interface (HCI). The theories of hand segmentation and the hand detection system are used to construct hand gesture recognition using Python and OpenCV. From the database, the training images are labelled with different names. Each of the images is converted to a binary feature vector. The feature extraction procedure is carried out from the picture collected from real-time video of hand signs using camera and Convolutional Neural Network (CNN). These features are compared with the features of database photos and the system produces output based on the predicted highest similarity. Without a fixed or monochromatic background, this model offers satisfactory accuracy and can be used with the help of an application. The camera is used to record video of the hand gestures of the person, which is then analyzed and converted into textual description. The output is converted to speech, which is heard by the user. The proposed system includes sign language recognition of numbers, alphabets and some common words. Image processing algorithms along with neural networks are used to map the gesture to appropriate text in the training data and hence raw images/videos are converted into respective text that can be read and understood. Such a protocol will undoubtedly be very helpful for bridging the communication gap between those with speaking and hearing abilities and those without them, especially when combined with a large source database.

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 Keywords

American Sign Language, Human- Computer Interface, Convolutional Neural Network

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Creative Commons Attribution 4.0 and The Open Definition

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This paper presents the improvement in the cleanliness of the machine part of the crankshaft in the machine shop which belongs to the value stream of the compressor and braking system. The machined parts of the crankshaft are taken for the Millipore test to calculate the amount of dust particles present in the machined part. The values obtained from the Millipore test are taken for process capability analysis through which the process capability index value is less than the standard specific limit. To increase the process capability index value the washing machine of the machined parts are audited, and the defects are rectified. The washed machined parts are taken for the Millipore test which results in a process capability index value increased than before.

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 Keywords

Machined Crank shaft, Process Capability, Millipore Test.

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Creative Commons Attribution 4.0 and The Open Definition