Volume 11 | Issue 6 |

 Abstract

Background: The corona virus disease 2019(COVID-19) pandemic (officially declared on the March 11, 2020), and the resulting measures, are impacting daily life and medical management of cancer patients. This study is intended to evaluate the association between COVID 19 pandemic and cancer survival, and to explore the prevalence of co-morbidities in cancer patients. Methods and materials used: The retrospective study was carried out in the oncology department for a period of six months. The data were collected from patient history and, Medical Record Department. A total of 150 subjects were included in this study with 75 Pre-pandemic cancer patients and similar age , gender matched 75 Post- pandemic patients . Charlson Comorbidity Index (CCI) is used to assess the survival rate of cancer patients. Results: Based on the comparison of survival rate of Pre-pandemic and Post-pandemic cancer patients, the Pre-pandemic cancer patients have mild survival rate (44%) and the Post-pandemic cancer patients have moderate survival rate (62.67%). Both males and females among the study population have moderate survival rate of 44.12% and 51.22% respectively. By comparing the survival rate of breast cancer patients with other cancer patients, both the groups have moderate risks of survival for next 10 years (46.34%) and (48.62%) respectively. Metastatic cancer patients have severe risks of survival (59.02%), whereas other cancer patients have moderate risks of survival (100%) for the next 10 years. Conclusion: The prevalence of co-morbidities in cancer patients has increased after the covid-19 pandemic. Our finding reveals that the risk of survival of cancer patients has increased from mild to moderate level after covid-19 pandemic.

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 Keywords

Co-morbidities, COVID-19, CCI, Breast cancer, Metastasis, Cancer survival.

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Creative Commons Attribution 4.0 and The Open Definition

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The menopausal transition marks a time of great variability in reproductive hormones, and this variability can be responsible for specific symptoms, such as hot flashes and mood disturbances. Once a woman who is more than 45 years old has gone for 12 months without a menstrual period, she is considered to be menopausal and has consistently low circulating estradiol and elevated gonadotropins. Estrogen is the most efficacious therapy for bothersome vasomotor symptoms. Although estrogen exerts clear-cut protective effects on the cardiovascular system in premenopausal women, medical evidence does not support its use for the prevention of cardiovascular disease soy protein and isoflavones contained in soy foods can improve muscle and bone density quality and reduce body weight. It is considered a breakthrough in preventing osteosarcopenia and obesity that may occur after menopause. Polycystic ovary syndrome (PCOS) is an oxidative state resulting in ovarian dysfunction. Licorice is one of the natural antioxidants used for the treatment of infertility. Present review of the plants showed a wide range of pharmacological activity in anxiolytic relax the clinical disease, such as anti-inflammatory, anxiety and antioxidant. In addition, Passiflora incarnata L. affects menopause symptoms such as vasomotor symptoms, insomnia, and depression The researchers concluded sesame ingestion benefits postmenopausal women by improving blood lipids, antioxidant status,and possibly sex hormone status Fenugreek seeds (which are rich in phytoestrogens) may be the alternative strategy to treat the above mentioned menopause induced deficits. This study was designed to evaluate the role of Fenugreek seed extract on menopause induced impaired memory and hippocampal damage using ovariectomized rat model.

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Fenugreek, menopausal women, meta-analysis, protocol, vasomotor symptoms [11:32, 6/1/2023] Seema Kurhe Pharm: Menopause, Menopausal women, Vasomotor hot flash, Post menopausal hot flash, Herbal medicine, Licorice

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This research paper aims to examine the role and challenges faced by Anglo-Indian troops during the early colonial period in India. By exploring historical archives and academic studies, we seek to gain a deeper understanding of the complex dynamics between European powers, indigenous forces, and the Anglo-Indian community, shedding light on the socio-political landscape of British India. This research paper examines the significance of Anglo-Indians in the early colonial settlements in India and the reasons behind their recruitment and subsequent exclusion from various roles within the British East India Company. This paper explores how the Anglo-Indian community emerged, its contributions to the military, and the complexities of its relationship with the British and indigenous powers. This paper also discusses the discriminatory policies and shifts in attitude towards Anglo-Indians by the British, analysing their impact on the community's social standing and political influence.

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Anglo-Indians community, Army, Country-born, Nepotism, Policies towards Anglo-Indians, Topasses.

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Creative Commons Attribution 4.0 and The Open Definition

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Ritu means season in Sanskrit, while Sandhi denotes the meeting of two things. This means that Ritusandhi is the meeting point of two Ritu. The first goal of Ayurveda is "Swasthyarakshan," or health maintenance. To achieve this goal, the great Trio provides regimens for different seasons as well as day-to-day living. There are separate chapters on Dincharya and Ritucharya. Ritu is a season. The year is divided into two halves in Ayurveda literature: Uttarayana and Dakshinayana. Each Ayana is further subdivided into three Ritu. As a result, there are a total of six Rituare in one year. Different foods and practises are recommended for each Ritu. Vagbhatta describes Ritusandhi towards the end of Ritucharya. Ritu Sandhi is a moment when the seasons collide. Ritusandhi lasts one week in the previous season and one week in the next season. This review article discusses the significance of Ritu and Ritusandhi in today's world. This is a review of Samhitokta Ritu and Ritusandhi. This review essay discusses the significance of Ritu and Ritusandhi in the current context. References and pertinent information are obtained from Ayurveda literature, the internet and research publications. distinct Ritu have distinct environmental circumstances. These diseases have an immediate impact on the human body.

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Ritu, Ritusandhi, Ritucharya, Swasthyarakshana, Uttarayana, Dakshinayayana, Uttarayana, Dakshinayayana.

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Creative Commons Attribution 4.0 and The Open Definition

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Background: Functional training contributes to different systems of the body with functional exercises in different parts of the body (covering the whole body, developing universal motor skills, applied in multiple motion planes) through intensive, short and constantly changing sessions. Functional training, simultaneously increasing athletes' muscular endurance, hypertrophy, power and strength, also creates an excellent impact to improve aerobic power and anaerobic capacity. Aim: Aim of the study is to find out the influence of functional training on biomotor skills in tennis players. Objective of the Study: To Evaluate the Effectiveness of Functional training on Biomotor skills in Tennis Players by using biomotor performance components, including the10-m Speed Test, Vertical Leap Test, Sit down Test, Grip Force Test, Agility Test (T Test) and Anaerobic Power test. Method: The study was continued with 10 persons in CG and 10 persons in EG. Volunteer participants were selected from tennis club; Girl athletes between 14-18 years old who had been playing tennis for at least 6 months were preferred. Group A was given 8 weeks of routine training program and Group B was given 8 weeks of Functional training program. Data Analysis was done prior to the beginning of the training session and post assessment done at the end of 8 week. Result: When comparing the pre-test-post-test values in terms of inter-group which applied the 8-week routine tennis and functional training program, a significant difference was found in favour of the experimental group. Conclusion: The present study concluded that, functional training is effective in improving biomotor skills in girl tennis players.

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 Keywords

: Biomotor ability, Functional training, Tennis player

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Creative Commons Attribution 4.0 and The Open Definition

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Naranjos scale, Adverse drug reaction, Prescribing pattern, Psychiatry, Anti-Psychotics, Anti-Depressants

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Creative Commons Attribution 4.0 and The Open Definition

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This research paper presents a detailed and comprehensive study on the valuation of plant and machinery, with a specific focus on power press machines used in the automobile manufacturing industry. The primary objective of this research is to gain a deeper understanding of the valuation process and accurately calculate the fair market value of these machines. The study involves conducting a thorough analysis of the machines' capacity, capabilities, and specifications, while also considering industry-specific factors and regulations that significantly impact their value. The research paper concludes with a comprehensive and accurate determination of the fair market value of the power press machines, which serves as a valuable tool for financial and decision-making purposes within the automobile manufacturing industry. The findings from this research contribute to the existing knowledge on plant and machinery valuation, offering practical implications for asset management and financial planning. Ultimately, this research expands our understanding of the complex process of plant and machinery valuation and provides insights that can assist industry professionals in making informed decisions regarding these valuable assets.

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Plant and Machinery valuation, Power press machine, Automobile, Financial planning.

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Creative Commons Attribution 4.0 and The Open Definition

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Several transdermal therapeutic methods have been developed for topical application onto the intact skin surface to manage drug distribution and its subsequent penetration through the skin tissue in order to offer continuous medication infusion via an intact skin. A viable alternative to systemic medication delivery is transdermal method. The ethanolic phospholipid vesicles known as "ethosomes" are employed mostly for transdermal medication administration. Since ethosomes penetrate the skin more quickly than liposomes do, they can often be utilised in place of liposomes. Due to their enhanced skin penetration, improved drug delivery, greater drug entrapment efficiency, etc., ethosomes have attracted researchers' attention.

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Ethosomes, Phospholipids, Transdermal, Skin permeation

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Creative Commons Attribution 4.0 and The Open Definition

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This research paper presents the design and development of a manually controlled trash collecting bot that integrates an Android app developed using MIT App Inventor. The bot incorporates a four-wheel drive mechanism, Bluetooth connectivity, and a robotic arm for efficient garbage collection. The system is controlled using an ARDUINO UNO board, and human intelligence is required for garbage detection. The primary objective of this study is to create a versatile and effective trash collecting bot that can navigate various terrains, establish wireless communication, utilize a robotic arm for trash collection, and leverage human perception for garbage identification.

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Trash Picking robotic arm, Blue control app, and soft catching gripper.

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Creative Commons Attribution 4.0 and The Open Definition

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Tulsi drop preparations containing extracts of various Ocimum species are available in the market. These are extensively used for their immunomodulatory properties. Eugenol is one of the active biomarkers of Ocimum species. In the current study content of eugenol in three marketed Tulsi drop preparations was determined using a simple UV spectrophotometric method. The linear regression equation y = 0.0235x + 0.0065 was used to determine the amount of eugenol at 282 nm. Different Tulsi drop preparations were found to have variable content of eugenol.

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Eugenol, UV-visible spectrophotometry, Tulsi drops, Immunomodulators

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Creative Commons Attribution 4.0 and The Open Definition