Volume 8 | Issue 6 |

 Abstract

ABSTRACT Nanotechnology is a developing branch of pharmaceutical sciences wherein the particles extend in nanosizes and turn out to be more responsive when contrasted with their unique counter parts. In the past numerous years, the utilization of synthetic concoctions and physical strategies were in mould; however, the acknowledgment of their toxic impacts on human well-being and condition influenced serious world view for the researchers. Presently, green synthesis is the watch word for the combination of nanoparticles (NPs) by plants or their metabolites. This innovation is particularly compensating as far as decreasing the poisonous quality caused by the conventionally integrated NPs. In this review, we cover the perspectives by which metal particles can be integrated from green methods in the perspective of green methods utilized in the NPs combination. In the green strategies, plant metabolites and natural substances are utilized to orchestrate the NPs for the pharmaceutical and other applications. Some characterization methods are also reviewed along with applications of NPs.

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KEYWORDS: Green synthesis; Nanoparticles; Metal nanoparticles; Green synthesis of nanoparticles

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ABSTRACT: Objective: Mouth dissolving films these are novel dosage forms it comes under fast dissolving drug delivery system. It disintegrates or dissolves within the oral cavity. It does not require water for administration so that it is convenient for medications for the pediatric and geriatric patients which have the difficulty in swallowing. This research work was aimed to enhance the oral bioavailability and provide faster onset of action of Tadalafil by formulating its mouth dissolving film (MDF). Method: The MDF of Tadalafil was prepared by solvent casting method. Tadalafil it is a BCS class II and it has the oral bioavailability of about 28%. HPMC k-15, Xanthan gum, Sodium alginate (film forming agent), Glycerol (plasticizer), Tween 80 (solubilizing agent), Citric acid (saliva stimulating agent), Sucrose (sweetening agent), vanillin (flavoring agent), Propyl paraben (preservative). The formulation was evaluated for weight variation, thickness, folding endurance, drug content, disintegration time and in-vitro dissolution study stability study. Conclusion: Based on the results F2 was showed enhanced bioavailability and rapid onset of action as compared to other dosage form.

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Keywords: Tadalafil, Mouth Dissolving Film, Bioavailability.

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A huge number of projects have undergone distress due to the slowdown in Indian economy. As a result the Indian banking system has been increased in NPA (Non-performing Assets) and restructured real estate projects during the recent years. With degradation in value the distressed assets don�t produce any profit in economy. Financial distress is a trending topic these days in finance and the project�s health is very important for investors as well as management. Investors deposit money in those projects which are financially healthy as risk of default is minimized for them, while management must be able to identify causes of distress which can be controlled by taking different measures. This paper deals with the elements of project financial distress as its major signs and sources as well as it suggests ways to eliminate the consequences. This result provides an effective way to resolve financial distress by restructuring it. Restructuring a project is always a better option in comparison with liquidation if the project has undergone distress. This paper also shows that restructuring can be looked at in three broad categories: event oriented process oriented and technical oriented. This paper describes each category: their identification in live case study project and elimination process. I integrate the theory of financial distress into a real estate project initial model and examine a financial distressed phenomenon from capital market perspective and have made a restructured financial model based on different restructuring approaches- Additional loan, Debt Curtailment, Equity share, Debt-Equity tradeoff, Selling of shares and discussing about the profitability for each approach considering their pessimistic and optimistic value and the risk factors involved. Comparing all the approaches this paper suggests about the most suitable model that can be adopted for maximum profitability.

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Debt Restructuring, Financial distress, Non Performing Assets, Project financing

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A brief introduction to literary criticism and literary theory are given at the start. Then the indication of the word� Literary Criticism? and (literary theory) alongside with the root and advancement must be analyzed. Modern literary criticism is written in a variety of genres, including the article, review, survey, essay, literary profile, and bibliographical explanation. In any genre, the critic must be, in a sense, a political thinker, sociologist, and psychologist, as well as a literary historian and aesthetician. Additionally, this paper examines various critical, literary concepts and finally the conclusion is drawn by means of the review of literature indicated.

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Literary theory, criticism, traditional critical theories structuralism, formalism, feminism, deconstruction, modernism.

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To study self-control, smartphone overuse and their association among 120 late adolescent students of aged 18-21 years. For collecting and analyzing participants� data, used PMPU questionnaire (Billieux et al., 2008) for smartphone overuse and BSCS (Tangney et al., 2004) for self-control. The findings were unveiled that gender group differences were significantly found in dangerous use (t=3.91; p<.05), dependent use (t=4.71; p<.05), financial problems (t=4.19; p<.05), and self-control (t=5.62; p<.05) respectively. Stream group differences were significantly found in dangerous use (t=4.88; p<.05) and dependent use (t=2.25; p<.05) but no stream group differences were found in self-control. It was evidenced that self-control was found as a negative correlation with dangerous use (r=-.270; p<.05), prohibited use (r=-.312; p<.05), dependence use (r=-.725; p<.01), and financial problems (r=-.405; p<.01). Further it was evidenced that self-control was found to negatively and significantly predict dangerous use (R2=7.3%; F=9.30; t=-3.05; p<.01), prohibited use (R2=9.7%; F=12.73; t=-3.57; p<.01), dependent use (R2=52.5%; F=130.54; t=-11.43; p<.01), and financial problems (R2=16.4%; F=23.20; t=-4.82; p<.01) through regression analysis. This study has been concluded that students who use smartphones excessively having low self-control over their gadgets.

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Gender, Late Adolescent Students, Self-Control, Smartphone Overuse, Stream

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Profitable investment into Real Estate residential projects requires a realistic and more practical approach for evaluating its financial performance and efficiency. Uncertainty in the residential real estate has always been an issue. Till date, financial return of a residential project in India is calculated using a Discounted cash flow model (DCF) which gives a single point value (deterministic result), not including risks and uncertainties. Addressing risks and uncertainties into otherwise deterministic models avoids irrelevant and impractical financial decision and help in framing a more feasible forecasting model. The objectives of this thesis is to develop a suitable investment model for residential real estate along Dwarka Expressway, Gurugram, India using both deterministic and probabilistic financial analysis models- Discounted cash flow (DCF) model and Monte Carlo Simulation respectively. Master plan analysis and real estate market analysis led to selection of �three� different stretches on Dwarka Expressway for which forecasting investment models is developed for better investment decisions. The study divides different risks involved in the study area under five categories- economical, technological, political, legal and social risks. These identified risks are then classified under 7 quantifiable major risks categories that have an impact on the cash flow - Sales risks, Market growth risk, Leverage Risk, Development risk, Inflation risk, Interest rate risk and Taxation risk. These risks with their range of possible values are incorporated into DCF model through Monte Carlo simulation (Probabilistic Model) and a comparison is made between their financial returns for choice of investing along Dwarka Expressway.

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Residential Real Estate, Risk Identification and assessment, Forecasting Investment Model, Monte Carlo Simulation

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The two varieties of pumpkin seeds such as orange pumpkin seed (OPS) and white pumpkin seed (WPS) were analyzed with their ethanol extracts for the estimation of fatty acid components through GC-MS analysis. 37 compounds were analyzed in total in both OPS and WPS where about 19 compounds were pinpointed to be present in OPS, 25 compounds in WPS and about 8 compounds to be present common in both OPS and WPS. The peak area % concentration obtained from analysis were compared with the known peak area % concentrations of WILEY8.LIB and the results were interpreted. Some of the compounds determined to be present in higher concentration in OPS include were Propane 1,1,3-triethoxy- (6.58 %), Hexadecanoic acid, 1-(hydroxymethyl)-1,2 ethanediyl ester (9.38 %), 9,12-Octadecadienoyl chloride, (Z,Z)- propanetriyl ester, (E,E,E)- (17.59 %), 9-Octadecenoic acid, 1,2,3-propanetriyl ester � (19.19 %), Squalene (21.33 %) and those identified in WPS include Beta.-Sitosterol (5.10%), 9-Octadecenoic acid,1,2,3-propanetriyl ester (E,E,E) (5.65%), Chondrillasterol (7.30%), Propane, 1, 1, 3- triethoxy- (7.50%), Bicyclo[10.1.0]tridec-1-ene (40.55%). Among them biological activities of some of the important compounds are suggested. This study thus offers the base for using OPS and WPS as an herbal supplement.

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Pumpkin seeds, GCMS, Fatty acids

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The uses of biodiesel are increasingly popular because of their low impact on environment. However, it causes combustion problems in conventional diesel engine[CE]. Hence it is proposed to use the biodiesel in low heat rejection (LHR) diesel engines with its significance characteristics of higher operating temperature, maximum heat release, and ability to handle the lower calorific value (CV) fuel etc,. In this work, biodiesel from linseed was used as sole fuel in both versions of the combustion chamber. Engine with LHR combustion chamber was developed with ceramic coating on inside portion of cylinder head by partially stabilized zirconia of 0.5 mm thickness. The experimental investigations were carried out on a four stroke, single cylinder, DI 3.68 kW at a speed of 1500 rpm, In this investigation, comparative studies on performance parameters was made on CE and engine with LHR combustion chamber with different operating conditions of biodiesel with varied injector opening pressure and injection timing. CE showed compatible performance while LHR combustion chamber showed improved performance with biodiesel operation in comparison with pure diesel operation on CE.

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Alternate Fuels, Vegetable Oils, Biodiesel, LHR combustion chamber, Performance parameters.

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Creative Commons Attribution 4.0 and The Open Definition

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WiFi Pose Estimation, CSI, FCN, Deep learning, pi.

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Creative Commons Attribution 4.0 and The Open Definition

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Keywords: Sunderban, mangrove ecosystem, biosphere reserve, Amphan, blue carbon sink, community based conservation

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