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Volume 10 | Issue 5 |

Volume 10 | Issue 5 | Month  
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  Paper Title: GASTRO RETENTIVE DRUG DELIVERY SYSTEM

  Author Name(s): Mahesh P. Junghare, Dr. Amol Gayake, Dr. Lokesh G. Barde, Dr. R.S. Kalkotwar

  Published Paper ID: - IJCRT21X0033

  Register Paper ID - 219897

  Publisher Journal Name: IJPUBLICATION, IJCRT

  DOI Member ID: 10.6084/m9.doi.one.IJCRT21X0033 and DOI :

  Author Country : Indian Author, India, 423401 , Yeola, 423401 , | Research Area: Pharmacy All

Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT21X0033
Published Paper PDF: download.php?file=IJCRT21X0033
Published Paper PDF: http://www.ijcrt.org/papers/IJCRT21X0033.pdf

  Your Paper Publication Details:

  Title: GASTRO RETENTIVE DRUG DELIVERY SYSTEM

 DOI (Digital Object Identifier) :

 Pubished in Volume: 10  | Issue: 5  | Year: May 2022

 Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882

 Subject Area: Pharmacy All

 Author type: Indian Author

 Pubished in Volume: 10

 Issue: 5

 Pages: c405-c458

 Year: May 2022

 Downloads: 931

  E-ISSN Number: 2320-2882

 Abstract

The drug delivery system enables the release of the active pharmaceutical ingredient to achieve a desired therapeutic response. Conventional drug delivery systems (tablets, capsules, syrups, ointments, etc.) suffer from poor bioavailability and fluctuations in plasma drug level and are unable to achieve sustained release. Without an efficient delivery mechanism, the whole therapeutic process can be rendered useless. Moreover, the drug has to be delivered at a specified controlled rate and at the target site as precisely as possible to achieve maximum efficacy and safety. Controlled drug delivery systems are developed to combat the problems associated with conventional drug delivery. There has been a tremendous evolution in controlled drug delivery systems from the past two decades ranging from macro scale and nano scale to intelligent targeted delivery. The initial part of this review provides a basic understanding of drug delivery systems with an emphasis on the pharmacokinetics of the drug. It also discusses the conventional drug delivery systems and their limitations. Further, controlled drug delivery systems are discussed in detail with the design considerations, classifications and drawings. In addition, nano-drug delivery, targeted and smart drug delivery using stimuli-responsive and intelligent biomaterials is discussed with recent key findings. The paper concludes with the challenges faced and future directions in controlled drug delivery.


Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

controlled release dosage forms, pharmacokinetics, nano-drug delivery, smart and stimuli-responsive delivery, intelligent biomaterials

  License

Creative Commons Attribution 4.0 and The Open Definition



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ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
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ISSN and 7.97 Impact Factor Details


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ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
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