IJCRT Peer-Reviewed (Refereed) Journal as Per New UGC Rules.
ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 7.97 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(CrossRef DOI)
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Paper Title: GASTRO RETENTIVE DRUG DELIVERY SYSTEM
Author Name(s): Mahesh P. Junghare, Dr. Amol Gayake, Dr. Lokesh G. Barde, Dr. R.S. Kalkotwar
Published Paper ID: - IJCRT21X0033
Register Paper ID - 219897
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT21X0033 and DOI :
Author Country : Indian Author, India, 423401 , Yeola, 423401 , | Research Area: Pharmacy All Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT21X0033 Published Paper PDF: download.php?file=IJCRT21X0033 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT21X0033.pdf
Title: GASTRO RETENTIVE DRUG DELIVERY SYSTEM
DOI (Digital Object Identifier) :
Pubished in Volume: 10 | Issue: 5 | Year: May 2022
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Pharmacy All
Author type: Indian Author
Pubished in Volume: 10
Issue: 5
Pages: c405-c458
Year: May 2022
Downloads: 931
E-ISSN Number: 2320-2882
The drug delivery system enables the release of the active pharmaceutical ingredient to achieve a desired therapeutic response. Conventional drug delivery systems (tablets, capsules, syrups, ointments, etc.) suffer from poor bioavailability and fluctuations in plasma drug level and are unable to achieve sustained release. Without an efficient delivery mechanism, the whole therapeutic process can be rendered useless. Moreover, the drug has to be delivered at a specified controlled rate and at the target site as precisely as possible to achieve maximum efficacy and safety. Controlled drug delivery systems are developed to combat the problems associated with conventional drug delivery. There has been a tremendous evolution in controlled drug delivery systems from the past two decades ranging from macro scale and nano scale to intelligent targeted delivery. The initial part of this review provides a basic understanding of drug delivery systems with an emphasis on the pharmacokinetics of the drug. It also discusses the conventional drug delivery systems and their limitations. Further, controlled drug delivery systems are discussed in detail with the design considerations, classifications and drawings. In addition, nano-drug delivery, targeted and smart drug delivery using stimuli-responsive and intelligent biomaterials is discussed with recent key findings. The paper concludes with the challenges faced and future directions in controlled drug delivery.
Licence: creative commons attribution 4.0
controlled release dosage forms, pharmacokinetics, nano-drug delivery, smart and stimuli-responsive delivery, intelligent biomaterials

