Volume 11 | Issue 4 |

 Abstract

A series of bis-benzimidazole clubbed with pyridine were design (1-12) and reported their ADMET (Absorption, Distribution, Metabolism, Excretion, Toxicity) prediction studies. Bioactivity prediction, physicochemical properties, and toxicity profiles for designed benzimidazole derivatives studied by using Molinspiration, admetSAR, and Osiris property explorer online software's. To predict drug like properties and bioactivity score of design molecules, used Molinspiration web server. 'Lipinski's rule of five' is followed by all designed derivatives and can be considered as good oral drug. Prediction of Toxicity, drug relevant properties were calculated using Osiris property explorer software. Bioactivity prediction also shows good enzyme inhibition activity of designed compounds. Among designed compounds, some compounds show good predicted ADMET properties in terms of Gastrointestinal absorption.

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 Keywords

Benzimidazole; ADMET; Osiris, Molinspiration, Bioactivity

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Nickel catalysts have been widely used in various industrial processes, including hydrogenation and dehydrogenation reactions. In this study, we report the synthesis of nickel catalysts by coprecipitation method using nickel nitrate and sodium hydroxide as precursors and silica as a support material. The effect of different synthesis parameters, such as the nickel to silica ratio, pH, and temperature, on the morphology and catalytic performance of the nickel catalysts was investigated. The synthesized nickel catalysts were characterized by XRD, SEM, and FTIR techniques. The results showed that the nickel catalysts had a high surface area and uniform distribution of nickel particles. The nickel catalysts exhibited excellent catalytic activity for hydrogenation and dehydrogenation reactions. The superior performance of the nickel catalysts was attributed to the high dispersion of nickel particles on the silica support and the formation of nickel-silica interface. The coprecipitation method was found to be a simple, efficient, and scalable method for the synthesis of nickel catalysts with high catalytic performance. This study provides insights into the design and synthesis of nickel catalysts for various industrial applications.

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 Keywords

Nanotechnology, Nickel Catalyst, Catalytic Activity, Co-precipitation, Nanocatalyst

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Greenhouse effect is the phenomenon in which some gases that occurs in earth's atmosphere absorbs and traps solar heat. This keeps earth warmer than actual conditions. It is one of the most important causes which makes earth comfortable and habitable for living things. The gases responsible for this effect are oxides of carbon, CH4, nitrogen oxides, chlorofluorocarbons (CFCs), hydrofluorocarbons as well as ozone. These are mainly present in lower layer of atmosphere. Due to increased level of air pollution and industrial pollution, the amount of greenhouse gases is increased more than permissible limit that traps more heat and increases the temperature of atmosphere, which has major adverse effects on earth's atmosphere. Present study includes sources, effects and remedies of greenhouse effect.

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Greenhouse effect is the phenomenon in which some gases that occurs in earth's atmosphere absorbs and traps solar heat. This keeps earth warmer than actual conditions. It is one of the most important causes which makes earth comfortable and habitable for living things. The gases responsible for this effect are oxides of carbon, CH4, nitrogen oxides, chlorofluorocarbons (CFCs), hydrofluorocarbons as well as ozone. These are mainly present in lower layer of atmosphere. Due to increased level

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Construction materials we see today is the result of a progression in science, technology and process. The extraordinary chemical and physical properties of nano materials enable novel applications ranging from strength, energy conservation, and antimicrobial properties to self-cleaning surfaces. The manufactured nano composites are being considered for various uses in the sustainable construction industries. To achieve environmentally responsible nanotechnology in construction, it is important to consider the lifecycle impacts of nanomaterials on the health of construction workers and dwellers, as well as unintended environmental effects at all stages of manufacturing, construction, use, demolition, and disposal. In this paper we review smart applications of nanomaterials that improve conventional construction, and summarize potential toxicological effects to human health and environment.

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 Keywords

Concrete, Nanoparticles, Green synthesis, Bioavailability Environment

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

In order to preserve a sufficient resource base for future generations, sustainable development necessitates the most efficient and conservation-minded use of resources. There is no one best approach to accomplish it, nor is it a concept that can be readily described. However, the environment is emphasized because it provides the resource base for all of society. Biotechnology is one of the more recent scientific advancements that has a wide range of uses that can optimize resource use. It entails genetic engineering, which is the manipulation of organisms to carry out particular processes. In relation to the environment, In recent years, the "modern biotechnologies" of molecular biology and gene technologies--which contain ecological, social, and economic requirements--have grown significantly in importance in the grains sector. Other environmentally advantageous aspects of biotechnology include resource recovery and recycling as well as the disposal of hazardous waste. Due to the expansion of the resource base, these are equally important to sustainable development. In this situation, biotechnology serves as a means of better controlling biogeochemical cycles. However, using biotechnology may have some very serious downsides. Future potential for biotechnology are therefore being constrained by the high rates of extinction that are now occurring in plant and animal species.

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Biotechnology, Sustainable development, Environment

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In everyday life, there are many types of waste materials continuously generating from various causes like domestic waste, industrial waste, chemical waste, agricultural waste etc. The solid waste can be described as domestic garbage, electronic waste material, construction debris, sludge from industries and metallurgical sites, discarded materials in plants and mining etc. Some of the waste is disposable, some is decomposable and some is reusable. Though various waste treatment methods are available, these are insufficient due to rapid industrialization, continuously growing population and high standards of living society. Hence more effective methods are required. Present article is focused on various methods for solid waste management used in our country.

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wastes, domestic garbage, disposable, reusable, effective etc.

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Zirconia (ZrO2) nanoparticles have wide range of applications in various fields. The green synthesis of metal oxide nanoparticles provides an advantage over the chemical synthesis approach. Researchers are working on synthesis methods of plant extracts to produce cost-effective and eco-friendly nanoparticles. Plant tissues contains various phytochemicals i.e. phenolic compounds, flavonoids, alkaloids, saponins, and amino acids. These compounds act as reducing, capping and stabilizing agent during the formation of ZrO2 nanoparticles. In this review, we focus on the biosynthesis of ZrO2 nanoparticles using different parts of plant extracts. This review article has summarized research papers from 2018-2023 which describe the process of ZrO2 nanoparticles biosynthesis, characterization and their application in different fields.

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Metal oxide, Zirconia, Green synthesis, Phytochemical, Nanoparticles.

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Nanomaterials that can efficiently use carbon-dioxide from the air, capture toxic pollutants from water and degrade solid waste into useful products. Nanomaterials could help us to mitigate pollution. They are efficient catalysts and mostly recyclable. Now, they have to become economical for commercialization and better to replace present day technologies completely. To help slow the climate changing rise in atmospheric CO2 levels, Researchers have developed Nano catalyst harvesters that suck atmospheric pollutants and deploy it for industrial purposes. In this article we will discuss the review on causes drastic climate change and how Nanomaterials could combat the reduction in pollution.

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Nanotechnology and Climate Change: A Reviews

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Abstract Tourism is a vital driver of socio-economic growth, cultural exchange, and regional development. In Bihar, a state with rich historical and cultural heritage, tourism offers immense potential for sustainable development. The state is home to globally significant heritage such as the Mahabodhi Temple at Bodh Gaya and Nalanda University, along with major Hindu, Jain, and Sufi religious sites. Despite this potential, Bihar has faced challenges in converting its heritage into sustainable tourism outcomes, including poor infrastructure, weak branding, and environmental vulnerabilities. This paper evaluates the challenges and prospects of sustainable tourism in Bihar by integrating data analysis, maps, and stakeholder perspectives. It uses a geographical framework supported by secondary data from government reports, census statistics, and international guidelines. The findings show that while domestic tourism has steadily grown, foreign tourist arrivals remain low. Opportunities exist in expanding eco-tourism, cross-border circuits with Nepal, and community-based tourism. The paper concludes that sustainable tourism in Bihar requires infrastructure development, institutional reforms, community participation, and effective policy implementation aligned with global best practices.

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Tourism Geography, Sustainable Tourism, Bihar, Cultural Heritage, Pilgrimage Tourism, Eco-tourism, Policy Planning

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Creative Commons Attribution 4.0 and The Open Definition

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Information and Communication Technology (ICT) tools have significantly reshaped education systems around the globe by introducing innovative methods for teaching and learning. This research explores the role and effectiveness of ICT tools in higher education within Assam, India, with particular emphasis on their influence on instructional practices, student involvement, and institutional administration. Adopting a mixed-methods approach, the study integrates quantitative survey data from college students and faculty in Assam with qualitative insights gathered through interviews and case studies by various researchers. The results indicate that ICT tools contribute to greater student engagement, support personalized learning experiences, and enhance administrative processes. However, barriers such as poor infrastructure, low digital literacy, and financial limitations continue to impede their widespread implementation. To address these challenges, the study recommends expanded investment in ICT infrastructure, comprehensive teacher training, and policy changes aimed at promoting equitable access. Overall, the research highlights the transformative capabilities of ICT in Assam's higher education landscape, while also identifying key areas that require attention.

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 Keywords

ICT, college education, Assam, digital tools, teaching-learning process, infrastructure challenges

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Creative Commons Attribution 4.0 and The Open Definition