Volume 12 | Issue 11 |

 Abstract

Identification And Evaluation Of Some Known Impurities In Active Pharmaceutical Ingredients Of Polmacoxib Using Rp-Hplc

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Identification And Evaluation Of Some Known Impurities In Active Pharmaceutical Ingredients Of Polmacoxib Using Rp-Hplc

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A REVIEW ARTICLE ON RECENT ADVANCES IN THE PHARMACOLOGICAL DIVERSIFICATION PYRIDINE DERIVATIVES ABSTRACT: Pyridine derivatives are the most common and significant heterocyclic compounds, which play an important role in various fields ranging from medical to chemo sensing applications. antioxidant, antiglycation, analgesic, antiparkinsonian, anticonvulsant, anti-inflammatory, ulcerogenic, antiviral, and anticancer activity. Furthermore, these derivatives have a high affinity for various ions and neutral species and can be used as a highly effective chemo sensor for the determination of different species. In this review article contain various biological activities, synthesis and pyridine containing drugs. Pyridine derivatives possess different biological activities such as antifungal, antibacterial, drugs. Pyridine derivatives play important role in bio-imaging applications for the diagnosis for various diseases. Pyridine-based macromolecules have greater potential for the efficient and specific delivery of drugs.

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Key words; Nitrogen containing compounds, biological activities, synthesis of pyridine, pyridine containing drugs.

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The study of Sacred Groves were carried out from Banali which is located in Banali village of Jath taluka in Sangli district. These Sacred groves are protected by local community through social traditions and taboos that incorporate spiritual and ecological values. These groves harbors many species of the plants and animals and rich in biodiversity. This is a small Sacred grove having an area of 27 acres with temple of Godess Banashankari. The area around the temple is surrounded by small hills. The population of tree cover near the temple is fairly good and well managed by the trust. The soil is blackish and fertile. This area is also called Banashankuri Ban'. It is owned by "Banashankari Devsthan Trust" . Banali village is located at a distance of 11 km from Jath city. This place in the drought village is a beautiful tourist spot. There are big trees around the temple with 20 to 25 acres are covered with large number of trees. The villagers perform annual rituals and ceremonies to appease the presiding deities and to ensure the well-being of the community. During the study area from this Sacred Grove we reported 41 species of plants from 27 families and 32 genera. It forms typical plant diversity within these sacred groves.

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Sacred Groves, plant diversity, Banshankari, Banali, Sangli.

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Tumors, cysts, and stones of the kidneys are among the serious problems in public health. It is critical to diagnose them early and accurately to achieve successful treatment. The current work aims to produce a web-based application for analyzing kidney CT scans by using deep learning techniques, based on a method known as CNN, in which the classification between Tumor, Cyst, Stone, or Normal occurs. The system makes further classification of renal cell images into predefined five classes in order to identify the malignancy level when a tumor is detected. The CNN model is trained based on a dataset 1 created from kidney CT scans sourced from Kaggle. The system designed by this approach offers an upload interface for images and provides diagnostic results in a very user-friendly manner. This project helps in diagnosing earlier and aids doctors to devise treatment planning which improves the management of kidney health care and the care of patients.

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Kidney disease diagnosis, Convolutional Neural Network, CT scans, Deep Learning, Tumor classification, Kidney health management.

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The Metaverse, where digital experiences blend seamlessly with our daily lives, luxury fashion has taken a bold step into virtual reality. This study dives into the fascinating realm of virtual luxury, focusing especially on virtual jewellery, to explore how these digital treasures are crafted, acquired, and cherished in online environments. Virtual jewellery represents a unique mixture of art, technology, and identity, providing consumers with new ways for self-expression and status display. This research explores the how the fashion industry is paving it's path in the realm of virtual luxury and fashion, particularly in jewellery. The research also highlights technological advancements that facilitate the creation of high-quality virtual jewellery and examines the economic opportunities for luxury brands in this growing market. Additionally, this study analyses the potential environmental benefits of virtual jewellery, considering the reduction of physical resource consumption and waste. The findings aim to provide comprehensive insights into the evolving concept of luxury in the Metaverse, demonstrating how virtual jewellery is redefining traditional notions of value and prestige.

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Metaverse, Virtual Jewellery, Luxury, Digital Treasures, Technology.

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The purpose of this study is to examine the Effectiveness of Adolescence Education Programme on Knowledge and Awareness among Govt. College. The method like descriptive survey was followed. In a quantitative method, the researcher collect, analyze and interpret varied kinds of numerical data obtained from the subjects. The sample consisted of 120 B.Ed. students. The results indicate a significant improvement in knowledge among the intervention group participants. The pre-test mean score was 12.5, which increased to 17.8 post-intervention. This represents a 42.4% increase in knowledge. The SD was 2.1 pre-test which increase to 2.5 post test. This represents 0.4 increased, the results show a significant improvement in awareness among the intervention group participants. The pre-test mean score was 10.2, which increased to 14.5 post-intervention. This represents a 42.1% increase in awareness. The SD was 1.9 pre-test which increase to 2.2 post test. This represents 0.3 increased. . In the area of adolescent education, particularly in the area of teenagers' understanding of adolescence, the study represents a significant advancement.

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Knowledge, AEP, Awareness, Adolescent, Education

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Abstract: In today's fast-paced world, stress has become an inevitable part of life. From work pressures to personal responsibilities, societal expectations, and the challenges of navigating daily life, stress can easily overwhelm an individual. However, when stress becomes chronic or poorly managed, it can have serious consequences for mental health. Stress is a common physiological and psychological reaction to perceived difficulties, and long-term exposure to it can have a serious negative influence on mental health. The need for efficient stress management strategies has been brought to light by the rising prevalence of stress-related illnesses like anxiety, depression, and burnout. This essay examines the detrimental effects of stress on mental health and looks at different stress-reduction techniques. The efficiency of various methods in lowering stress and enhancing mental health is evaluated, including cognitive-behavioural therapy (CBT), mindfulness-based stress reduction (MBSR), exercise, relaxation techniques, and social support. Furthermore, the function of community-based and organizational interventions in promoting resilience is investigated. The study highlights the value of a comprehensive strategy that incorporates environmental and personal coping mechanisms to reduce stress and enhance coping. This article explores the nature of stress, its impact on mental well-being, and the importance of stress management interventions in promoting mental health.

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stress, mental health, intervention, burnout, stress management, behaviour , health

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: In higher education institutions, students often face challenges accessing critical information related to courses, administrative support, and campus resources. Traditional methods, such as online portals and physical help desks, can be limited in terms of accessibility and efficiency. This paper proposes an AI-driven conversational chatbot that leverages natural language processing (NLP) and speech recognition technologies to deliver real-time information to students about college courses, events, and services. A unique feature of this system is its voice assistance in both Hindi and English, allowing broader accessibility among multilingual students. We discuss the design, development, implementation, and anticipated impact of the chatbot on student engagement and campus operations.

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AI Chatbot , Multilingual NLP, Voice Assistance , Higher Education , Student Engagement

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Climate change is ubiquitous and it has been incrementally increasing in the past decades. The impact of climate change varies from place to place and over time. It ranges from an increase or decrease in average temperature to significant damage to the built environment or a partial or complete disruption of social, economic, and environmental systems. It is a fact that these cannot be prevented and can only be managed to minimize loss of life, property and other related consequences. Coastal areas are highly susceptible to climate change majorly sea level rise, storm surges, soil erosion, coastal flooding etc. that poses significant threat to physical, social, economic and environmental aspects of coastal communities. Comprehensive and long-term strategies for disaster management and climate risk adaptation are required instantly, wherein community resilience becomes a perfect synthesis of a dual-pronged approach. Current disaster policies are short term focused and ignore the long-term benefits of building resilient communities. Here the authors have tried to explain the significance of resilient communities in disaster reduction and adaptation by delving into the conjectural knowledge of resilience and allege that resilience has to be an integral part of climate change adaptation and disaster risk reduction. The authors have attempted to analyze the inherent resilience of Chellanam, a coastal panchayath of Ernakulum District in Kerala, South India which is one among the worst-hit soil erosion coast of India, taking into account its disaster profile, risks and subsequent recent initiatives that lets the community evolve and plough on.

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Resilience, Disaster resilience, Coastal community resilience, Disaster risk reduction, Adaptation and mitigation.

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Introduction: This paper presents the case of a 40-year-old female residing in Delhi, India, whose X-ray of the submandibular gland area and a USG scan of the Thyroid / neck region revealed a salivary gland stone of about 8-9 mm in size. She had availed distal FTS energy healing sessions for the treatment of her condition. Method: The case records from both the healer and the patient are examined in-depth in this research using a case study methodology. Results: Healings were started 12 days after the initial diagnosis had taken place. On the third day of healing, the necessity for analgesics / painkillers was reduced. Surgery was suggested for the removal of the stone, due to it's awkward position. The first attempt at removing the stone through surgery was not successful due to persisting infection and pus in the tissue near the salivary gland. The surgery was rescheduled 2 weeks later, however the stone was nowhere to be found. A full recovery was observed within a span one month of starting energy healings. Conclusions: The energy healing protocols of FTS demonstrate effectiveness in treating a range of diseases, regardless of the distance between the healer and patient. These protocols are considered complementary and alternative medicine (CAM). It is important to conduct further research on this phenomenon using appropriate sample groups and methodologies. Additionally, it would be beneficial for healthcare professionals and their associates to receive training in holistic and non-contact energy healing techniques, thereby making treatment more accessible and cost-effective for patients.

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Submandibular Gland Area, Salivary Gland Stone, Feed The Soul (FTS) Energy Healing System

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