Volume 9 | Issue 1 |

 Abstract

Tinospora cordifolia (Giloy) is one of the important as well as very common herb which is normally used as common ingredient in various Falk, Ayurvedic, Unani and Siddha system of medicines. This review article mainly contains theinformationsoncultivation,Harvestingchemical constituents of Tinospora and the therapeutic benefits of this plant like Antiulcer, Antidiabetic, Antiinflammatory, Anticancer, Anti AIDS, Antiallergic activities.Giloy is considered as a most divine herb because of its various Ayurvedic uses. It is called as nectar/Amruta for its divine healing nature. Guluchi increases the immunity of the body. It fights against infecting organisms. The leaves of the plant in juice cure psychological disorder. The leaves are also used for swine flu treatment. It is also used for the treatment of fever due to infection.Guluchi is a remedy for diabetes. The traditional use of the leaves is to cure urine infection and stomach ulcer. Mixed with cow milk, Guluchileaves are used to cure leucorrhoea. It is also used as anti ageing juice. The plant oil is used to cure skin diseases and promote healthy skin. It brings down the high blood sugar. Guluchi purifies blood and levels the blood pressure.Traditionally, Guluchi is used to cure bowel problem. The starch prepared from it called �palo� is popular in India. The leaf juice mixed with cumin seeds is used to cure certain internal inflammation. It is also used to cure rheumatic pain. The leaf extract also used to cure jaundice and anaemia. This also can be used for the treatment of malarial fever and cough. It removes the toxins from the brain. It cures asthma and clears the respiratory tract. The juice of the leaf, root and stem helps in digestion. It also helps to bring down bleeding during menstruation. The juice is also used in the treatment of the cardiac disorder. Guluchi increases memory power. It enhances natural immunity in the human body. Guluchi increases appetite. It purifies milk in mothers. Guluchi adds strength and vigour to the body and removes the weakness. Because of the antioxidant nature, Guluchi is also used in the treatment of cancer. Giloy�s various uses and therapeutic applicability is precisely delineated in this paper.

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Introduction,tinospora cardifolia,Botonical descreption,Taxonomy,pharmacological Implementation

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: Power of speech is a blessing to human beings. It is an amazing pleasure to listen to people�s speech. Freedom of Expression has always been given utmost importance as a special right for the democratic, economic functioning of a society thereby enabling for good governance. Media plays a vital role in part of each and every human life and this paper aims at discussing about the role of media in Good governance. Media plays a significant role by providing information to the citizens about the evils related to social and economic conditions of life. It is a known fact that citizens cannot personally gather and collect all information�s to form his/her opinion. Access to internet and mobile phones is rising rapidly, not least in fragile states, but radio and TV remain the key sources of information for most people. Over the last couple of decades powerful changes in media markets have had a substantial impact on patterns of information, communication and governance: the number of media stations has rapidly increased. Political, religious, ethnic or other factional actors have stepped in, supporting media outlets to promote their agendas. Media serves as a medium of exercise of freedom of speech; hence it is rightly regarded as a �fourth estate�. Owing to the fact that Media plays a vital role in today�s society, this paper shall focus on the role of media in our democratic system of governance.

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Media, Good Governance, Participation, Rule of Law, Accountability.

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Creative Commons Attribution 4.0 and The Open Definition

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Pollution threat created by textile industries in India is becoming a major ecological concern. The waste generated by textile units is in form of post producer and post consumer. Post producer waste is produced during the manufacturing stage and dumped at landfill sites in large amount at the outskirts of cities. Usually this waste is seen as fiber, yarn, fabric and garment leftovers. As per environmental concern this waste can be managed by reduce, recycle, reuse and restore. To overcome the pollution created by these units a small research was carried out. Yarn waste was collected from textile units of Ahmedabad, Gujarat. The waste was segregated and mixed with potter�s clay as dough or sandwich layer and small pots were made by hand. Later on cooling effect and tensile strength was studied respectively in experiment.

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textile industry, yarn waste, post producer, cooling, tensile strength.

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In this paper we introduce ?_1 ?_2#rg-closed sets and ?_1 ?_2 #rg-open sets in bitopological spaces and established their relationships with some generalized sets in bitopological spaces. The aim of this paper is to introduce ?_1 ?_2#rg-continuous functions and ?_1 ?_2#rg-irresolute functions by using ?_1 ?_2#rg-closed sets and characterize their basic properties.

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?_1 ?_2#rg-closed; ?_1 ?_2#rg-open; ?_1 ?_2#rg-continuous; ?_1 ?_2#rg-irresolute.

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Abstract The concept of �?ood� is formulated with regard to human health and environmental impacts. flood that occurred at the end of that year. Heavy rains fell beginning vast flooding in most areas of Kerala , Karnataka to great destruction of livelihood of local societies. Natural hazard such as floods are not only caused by ordinary progressions but also by social activities. The flood recorded severe fatalities, injuries and exposed many susceptible to diseases. This paper study through considered the long-term impact of floods on human�s health as the special effects could meaningfully contribute to the universal burden of disease. Also, its outcomes are persistent hence need to be adequately realized and addressed through environmental. This study revealed susceptibility to flood tending disorders as spiritual suffering in the fighters is liable for a quota of all physical diseases.

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keywords; flood, , health; environmental, disease, death

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This paper consists of the description of the ideal principle of the realistic sublimity in the human life that represents the quality of a notion or a way of life being extremely good, beautiful and enjoyable that provides the harmony in human life to the state of supreme perfection and appropriateness. It is based on the oneness of the source of human life and oneness of human civilization and so it encourages accepting the perfect and the most appropriate way and notion of humanity that elevates the human life to the supreme status of virtues and values of an ideal human civilization. There are two aspects of sublimity, one related to nature and other related to arts and this paper focuses mainly on the description of the nature aspects and deals with the grand thoughts and strong emotions in the typical theme of the novel Gora.

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Sublimiy, realistic, ideological controversy, experience, excellence and righteousness, conflict, restriction, Brahmo.

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The automobile industry is one of the leading and largest industries in the world today. During the last decade, well-directed efforts have been made to provide phase lift to the automobile policy for realizing the sectors full prospective for the economy. Buyer behaviour occupies a pivotal place in marketing research. Enormous factors, including both internal and external to buyer, seem to extract an effective and efficient influence on the purchasing decisions of the buyer. An attempt is made in this present piece of research to find out the importance of peers on the buying behaviour of Two-wheelers with reference to buyers residing in and around Coimbatore city. Using purposive sampling technique 85 Two-wheeler buyers were identified and included as sample for the study. Peer Influence on Purchase Decision Making questionnaire developed by Clement.S. & Venkatapathy. R (2002) has been used to collect the data. Based on scope of the study initially the descriptive statistics was worked out and then F-test and Turkey�s test were used to analyse the data in this study. The findings reveal a positive trend on the influence of peers on the decision making of the purchases.

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Buyer behaviour, peer, automobile, purchase, decision making

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A thiocarbohydrazide Schiff based N''-[2-(hydroxyimino)-1,2-diphenylethylidene]-N'''-[(E)-(2-hydroxyphenyl)methylidene] thiocarbohydrazide prepared by condensing 2-hydroxybenzaldehyde and benzilmonoximethiocarbohydrazide. Its Cu(II), Zn(II), Cd(II) and Hg(II) complexes are synthesized and characterized on the basis of physical characteristics, elemental analyses PMR, FT(IR) spectrum and electronic absorption spectrum data. The spectrum data suggest coordination of Schiff base ligand with metal through nitrogen atoms of azomethine and oximino groups. On the basis of spectral and magnetic moments data suggests that Cu(II) complex is distorted octahedral and Zn(II), Cd(II) and Hg(II) are tetrahedral geometries

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Schiff base Metal complexes Spectroscopic study, 2-hydroxybenzaldehyde and benzilmonoximethiocarbohydrazide

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Natural Language Processing is a branch of artificial intelligence in which computational techniques are used to understand human languages in smart and useful way. Translation is a process through which historical scripts can be given to modern world. When compare with traditional language translation techniques, computational translation process makes it more convenient and can retrieve accurate results. Artificial Intelligence has significance in the area of linguistics. It helps to build a model for efficient and easier translation process. It makes scientific study of a language with its structure including grammar and syntax. Given study explores how Artificial Intelligence based computational techniques are helpful in natural language translation process by highlighting existing translation techniques in machine learning area and the process of developing new model. It also elaborates challenges in translation process.

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Artificial Intelligence, Machine Translation, Natural Language Processing, Linguistics.

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Natural Killer cells (NK Cells) act as the first line of defense against viral propagation. Being key players of innate immunity, they help in controlling viral propagation. In the ongoing COVID 19 pandemic scenario,Severe Acute Respiratory Syndrome Coronavirus2 [SARS COV-2] is known to infect humans. Following infection, viral replication machinery in order to maintain functional integrity, tweaks the host immune system in its favor. Even though the molecular tinkering might not completely render the virus immune-proof to the host immune system, but buys time to allow its multiplication and spread. SARS-COV-2 infected patients develop severe and uncontrolled immune response. This is associated with increase in several cytokines and migration of immune cells to the affected area. NK Cells of innate immunity are known to be attracted towards and kill an infected cell without much antigenic specificity.SARS COV2 evades first line-of-defense by inactivating NK Cells. The Spike Protein1 (SP-1) on the virus when presented by HLA-E, interacts with the inhibitory receptor CD94/NKG2A on NK cells to inactivate it, preventing destruction of the infected cells. Crosstalk between innate and adaptive immunity is also prevented as active NK cell stimulates TH1 (T-helper 1) cells expansion via induction of IL-12 by macrophage. Therapeutic intervention with NK cells in hyper-activated inflammatory COVID patient might be a significant strategy. The CD94/NKG2A receptor [C type lectin receptor that recognize carbohydrate moiety] can be used as a plausible target for carbohydrate moieties(of the virus) ,thereby preventing interaction with HLA-E and thus switching off inhibitory signals. Antibody dependent cell mediated cytotoxicity may also be a probable way. In this case, mAb(monoclonal antibodies) designed against SP1 protein can be produced; Fab of the mAb region binds to displayed SP-1 peptide by HLA-E ,and Fc region of the mAb binds to CD16A on NK cells and destroy the infected cell.

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 Keywords

SARS-CoV-2, NK cells, HLA-E, CD94/NKG2A receptor

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Creative Commons Attribution 4.0 and The Open Definition